Author

T. Carr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Immunology· 1 Zoology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Dubrovskiy· 1 shared A. Erb· 1 shared A. Local· 1 shared A. Shakya· 1 shared B. L. Kee· 1 shared C. E. Schwartz· 1 shared C. Gutierrez-Ibanez· 1 shared D. Naish· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A. Dubrovskiy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

How smart was T. rex? Testing claims of exceptional cognition in dinosaurs and the application of neuron count estimates in palaeontological research

K. R. Caspar, C. Gutierrez-Ibanez, O. C. Bertrand, T. Carr, J. Colbourne, A. Erb, H. George, T. R. Holtz, D. Naish, D. R. Wylie, G. R. Hurlburt

This paper revisits neuron count estimates for dinosaurs, identifies flaws in previous analyses, and argues for more integrative approaches to reconstruct Mesozoic dinosaur biology.

bioRxiv · Jan 10, 2024Zoology

Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in a Murine Model of T Acute Lymphoblastic Leukemia

T. Carr, S. McGregor, S. Dias, M. Verykokakis, M. M. Le Beau, H.-H. Xue, E. T. Bartom, B. L. Kee

This study shows that the timing of Lef1 mutations in a murine T-ALL model affects its role as a tumor suppressor or oncogene, highlighting the importance of mutational order in leukemogenesis.

bioRxiv · Nov 8, 2021 · PreprintCancer Biology

Small molecule allosteric inhibitors of RORγt block Th17-dependent inflammation and associated gene expression in vivo.

S. A. Saenz, A. Local, T. Carr, A. Shakya, S. Koul, H. Hu, L. Chourb, J. Stedman, J. Malley, L. A. DAgostino, V. Shanmugasundaram, J. Malona, C. E. Schwartz, L. Beebe, M. Clements, , J. M. Ellis

The paper develops three RORγt inhibitors that reduce Th17 differentiation and inflammation in vivo and inhibit tumor growth in PDAC organoids.

bioRxiv · Feb 19, 2021 · PreprintImmunology