Cell BiologybioRxiv
Reprogramming of Iron Metabolism Confers Ferroptosis Resistance in ECM-Detached Cells
J. He, A. M. Abikoye, B. P. McLaughlin…·Z. T. Schafer
This study shows ECM-detached cancer cells resist ferroptosis due to reduced free iron levels from altered iron metabolism, suggesting potential limitations for ferroptosis-based therapies.
DOI 10.1016/j.isci.2023.106827