Cancer BiologybioRxiv
Immunosuppressive tumor microenvironment of osteosarcoma
A. M. Taylor, J. Sheng, P. K. S. Ng…·C. C. Lau
This study identifies immunosuppressive mechanisms in osteosarcoma using single-cell and spatial transcriptomics, revealing interactions between MDSCs, T-cells, and tumor cells that promote an immunosuppressive microenvironment.