ImmunologybioRxiv
The Regulation of Nucleic Acid Vaccine Responses by the Microbiome
A. M. F. Johnson, K. Hager, M.-G. Alameh…·J. G. Kublin
This study shows the microbiome affects nucleic acid vaccine responses differently depending on the vaccine type, enhancing mRNA-LNP responses but suppressing DNA-prime/DNA-protein-boost responses.