BiochemistrybioRxiv
Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains
L. Guo, J. R. Mann, J. C. Mauna…·J. Shorter
The paper identifies short RNAs that prevent and reverse pathological fibrillization of RNA-binding proteins like FUS and TDP-43, showing therapeutic potential for ALS/FTD.
DOI 10.1016/j.molcel.2025.12.009