MicrobiologybioRxiv
A tRNA-acetylating toxin and detoxifying enzyme in Mycobacterium tuberculosis.
F. G. Tomasi, A. M. J. Hall, J. T. P. Schweber…·E. J. Rubin
The paper identifies a TA system in Mtb, TacAT, where TacT acetylates tRNAs to inhibit translation and Pth reverses this effect, showing Pth's essentiality is unaffected by TacAT's absence.
DOI 10.1128/spectrum.00580-22