Author

C. L. Dulberger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

E. J. Rubin· 6 shared E. C. Garner· 3 shared I. D. Wolf· 2 shared J. Zhu· 2 shared Q. Liu· 2 shared S. M. Fortune· 2 shared T. R. Ioerger· 2 shared A. Bowers-Barnard· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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6 shared papersMicrobiology

E. J. Rubin

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Author profile →

6 papers

Recent·Most cited

Tuberculosis treatment failure associated with evolution of antibiotic resilience

Q. Liu, J. Zhu, C. L. Dulberger, S. Stanley, S. Wilson, E. S. Chung, X. Wang, P. Culviner, Y. J. Liu, N. D. Hicks, G. H. Babunovic, S. R. Giffen, B. B. Aldridge, E. C. Garner, E. J. Rubin, , S. M. Fortune

The paper identifies resR as a target of positive selection in Mtb clinical isolates, linking its mutations to antibiotic resilience and treatment failure.

bioRxiv · Mar 29, 2022Microbiology

Antibiotic action revealed by real-time imaging of the mycobacterial membrane

M. G. Wuo, C. L. Dulberger, R. A. Brown, A. Sturm, E. Ultee, Z. Bloom-Ackermann, C. Choi, E. C. Garner, A. Briegel, D. T. Hung, E. J. Rubin, L. L. Kiessling

This study uses real-time imaging to observe how antibiotics affect mycobacterial cell envelope remodeling, revealing unique cellular responses and extracellular vesicle production.

bioRxiv · Jan 7, 2022 · PreprintMicrobiology

A tRNA-acetylating toxin and detoxifying enzyme in Mycobacterium tuberculosis.

F. G. Tomasi, A. M. J. Hall, J. T. P. Schweber, C. L. Dulberger, K. McGowen, Q. Liu, S. M. Fortune, S. Helaine, E. J. Rubin

The paper identifies a TA system in Mtb, TacAT, where TacT acetylates tRNAs to inhibit translation and Pth reverses this effect, showing Pth's essentiality is unaffected by TacAT's absence.

bioRxiv · Dec 20, 2021Microbiology

High-density transposon mutagenesis in Mycobacterium abscessus identifies an essential penicillin-binding lipo-protein (PBP-lipo) involved in septal peptidoglycan synthesis and antibiotic sensitivity

C. Akusobi, B. S. Benghomari, J. Zhu, I. D. Wolf, S. Singhvi, C. L. Dulberger, T. R. Ioerger, E. J. Rubin

bioRxiv · Jul 1, 2021Microbiology

Prophage-encoded phage defence proteins with cognate self-immunity

S. V. Owen, N. Wenner, C. L. Dulberger, E. V. Rodwell, A. Bowers-Barnard, N. Quinones-Olvera, D. J. Rigden, E. J. Rubin, E. C. Garner, M. Baym, J. C. D. Hinton

The paper identifies BstA, a prophage-encoded phage defense protein that suppresses phage epidemics through abortive infection, with self-immunity mediated by the anti-BstA element.

bioRxiv · Jul 13, 2020Microbiology

A conserved translation factor is required for optimal synthesis of a membrane protein family in mycobacteria

S. Fishbein, I. D. Wolf, C. L. Dulberger, A. Wang, H. Keshishian, L. Wallace, S. A. Carr, T. R. Ioerger, E. J. Rubin, E. H. Rego

This study identifies LepA as a conserved GTPase that enhances the synthesis of mycobacterial porins, affecting drug tolerance and membrane permeability.

bioRxiv · Dec 11, 2019 · PreprintMicrobiology