BiochemistrybioRxiv
Variable autoinhibition among deafness-associated variants of Diaphanous 1 (DIAPH1)
R. Lakha, A. M. Montero, T. Jabeen…·C. L. Vizcarra
This study investigates how deafness-associated DIAPH1 mutations affect autoinhibition and actin assembly, finding variable disruption of autoinhibition among mutants.
DOI 10.1021/acs.biochem.1c00170