Cell BiologybioRxivPreprint
The effect of magnesium on calcium binding to cardiac troponin C related hypertrophic cardiomyopathy mutants
K. Rayani, E. Hantz, O. Haji-Ghassemi…·G. F. Tibbits
This study investigates how magnesium affects calcium binding to cardiac troponin C mutants linked to hypertrophic cardiomyopathy, showing that Mg2+ competes with Ca2+ and modifies binding affinity.
DOI 10.1101/2021.05.12.443789