Enforced MYC expression selectively redirects transcriptional programs during human plasma cell differentiation
P. Vardaka, E. Page, M. Care, S. Stephenson, B. Kemp, M. Umpierrez, E. O'Callaghan, A. Mabbutt, R. Owen, D. J. Hodson, G. M. Doody, R. Tooze
This study shows that enforced MYC expression alters transcriptional programs and metabolic shifts during human plasma cell differentiation without causing transformation.
bioRxiv · Apr 18, 2024 · PreprintCell Biology