Author

K. R. Bewley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:non-human primate· 2 Organism:rat· 2 Research Focus:spatial domain detection· 2

Frequent Co-Authors

K. A. Ryan· 6 shared Y. Hall· 5 shared B. E. Cavell· 4 shared D. Ngabo· 4 shared N. S. Coombes· 4 shared R. Cobb· 4 shared R. J. Watson· 4 shared S. A. Fotheringham· 4 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

6 shared papersMicrobiology

K. A. Ryan

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 21, 2023

Evaluation of the cross reactivity of neutralising antibody response in vaccinated human and convalescent hamster sera against SARS-CoV-2 variants up to and including JN.1 using an authentic virus neutralisation assay

N. S. Coombes, K. R. Bewley, Y. Le Duff…·S. G. P. Funnell

This study evaluates neutralising antibody responses in vaccinated humans and convalescent hamsters against SARS-CoV-2 variants up to JN.1 using an authentic virus neutralisation assay, finding increased resistance to JN.1 in vaccinated individuals and specific neutralisation patterns in hamsters.

DOI 10.1101/2023.10.21.563398

humanmouse

𝕏 PostBluesky

MicrobiologybioRxivPreprintDec 24, 2021

Convalescence from prototype SARS-CoV-2 protects Syrian hamsters from disease caused by the Omicron variant

K. A. Ryan, R. J. Watson, K. R. Bewley…·Y. Hall

This study shows that prior infection with a prototype SARS-CoV-2 strain protects Syrian hamsters from Omicron-induced disease.

DOI 10.1101/2021.12.24.474081

mouseexperimental assay

𝕏 PostBluesky

MicrobiologyNature CommunicationsPeer-reviewedJan 4, 2021

Dose-dependent response to infection with SARS-CoV-2 in the ferret model: evidence of protection to re-challenge

K. A. Ryan, K. R. Bewley, S. A. Fotheringham…·M Dennis

This study investigates the dose-dependent response of ferrets to SARS-CoV-2 infection, showing protection against re-challenge and mild clinical disease.

DOI 10.1038/s41467-020-20439-y

non-human primateexperimental assay

𝕏 PostBluesky

PathologybioRxivDec 21, 2020

Immunological and pathological outcomes of SARS-CoV-2 challenge after formalin-inactivated vaccine immunisation of ferrets and rhesus macaques

K. R. Bewley, K. E. R. Gooch, K. M. Thomas…·M. Carroll

This study evaluates vaccine-enhanced disease in ferrets and rhesus macaques after formalin-inactivated SARS-CoV-2 vaccination, finding mild transient lung pathology but no significant enhancement.

DOI 10.1126/sciadv.abg7996

ratnon-human primate

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ImmunologybioRxivSep 25, 2020

Prophylactic intranasal administration of a TLR2 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model

P. C. Proud, D. Tsitoura, R. J. Watson…·M. W. Carroll

DOI 10.1016/j.ebiom.2020.103153

mouseexperimental assay

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MicrobiologybioRxivSep 17, 2020

Comparison of Rhesus and Cynomolgus macaques as an authentic model for COVID-19.

F. J. Salguero, A. D. White, G. S. Slack…·Tr

This study compares rhesus and cynomolgus macaques as models for mild to moderate COVID-19, showing similar viral replication, immune responses, and histopathology.

DOI 10.1038/s41467-021-21389-9

ratchicken / avian

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