Author

A. Malerba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

C. Trollet· 2 shared E. Negroni· 2 shared J. Dhiab· 2 shared V. Mouly· 2 shared A. Boulinguiez· 1 shared A. Ferry· 1 shared A. Mahoudeau· 1 shared B. Crisol· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersPathology

C. Trollet

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2 papers

Recent·Most cited

Different outcomes of endurance and resistance exercise in skeletal muscles of Oculopharyngeal muscular dystrophy.

A. Boulinguiez, J. Dhiab, B. Crisol, L. Muraine, L. Gaut, C. Rouxel, J. Flaire, H.-R. Mouigni, M. Lemaitre, B. Giroux, L. Adoux, B. SaintPierre, A. Ferry, V. Mouly, G. S. Butler-Bowne, , C. Trollet

This study compares the effects of endurance and resistance exercise on OPMD skeletal muscle in mice, finding that resistance exercise reduces PABPN1 aggregates and reverses muscle atrophy, while endurance exercise increases aggregates and collagen deposition.

bioRxiv · Jan 12, 2024Pathology

Guanabenz treatment improves Oculopharyngeal muscular dystrophy phenotype

A. Malerba, F. Roth, P. Harish, J. Dhiab, N. Lu-Nguyen, O. Cappellari, S. Jarmin, A. Mahoudeau, V. Ythier, J. Laine, E. Negroni, E. Abgueguen, M. Simonelig, P. Guedat, V. Mouly, , C. Trollet

This study shows that guanabenz acetate reduces PABPN1 aggregates and improves muscle function in an OPMD mouse model by modulating the UPR.

bioRxiv · Jul 24, 2018 · PreprintPathology