Author

F. Roth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:mouse· 1

Frequent Co-Authors

A. Carpenter· 1 shared A. Fradera-Sola· 1 shared A. Hillairet· 1 shared A. Mahoudeau· 1 shared A. Malerba· 1 shared A.-C. Gingras· 1 shared B. Cimini· 1 shared C. Reno· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

A. Carpenter

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pervasive mislocalization of pathogenic coding variants underlying human disorders

J. Lacoste, M. Haghighi, S. Haider, Z.-Y. Lin, D. Segal, C. Reno, W. W. Qian, X. Xiong, H. Shafqat-Abbasi, P. Ryder, R. Senft, B. Cimini, F. Roth, M. Calderwood, D. Hill, , M. Taipale

The paper develops a high-throughput imaging platform to assess the functional impact of missense variants on protein localization, finding that mislocalization is common in pathogenic variants.

bioRxiv · Sep 5, 2023Cell Biology

ZNF524 directly interacts with telomeric DNA and supports telomere integrity

H. Braun, Z. Xu, F. Chang, N. Viceconte, G. Rane, M. Levin, L. Lototska, F. Roth, A. Hillairet, A. Fradera-Sola, V. Khanchandani, O. Dreesen, Y. Yang, Y. Shi, F. Li, , D. Kappei

This study identifies ZNF524 as a telomere-binding protein that maintains telomere integrity by supporting TRF2/RAP1 localization and preventing DNA damage and recombination.

bioRxiv · Nov 30, 2022Cell Biology

Guanabenz treatment improves Oculopharyngeal muscular dystrophy phenotype

A. Malerba, F. Roth, P. Harish, J. Dhiab, N. Lu-Nguyen, O. Cappellari, S. Jarmin, A. Mahoudeau, V. Ythier, J. Laine, E. Negroni, E. Abgueguen, M. Simonelig, P. Guedat, V. Mouly, , C. Trollet

This study shows that guanabenz acetate reduces PABPN1 aggregates and improves muscle function in an OPMD mouse model by modulating the UPR.

bioRxiv · Jul 24, 2018 · PreprintPathology