Author

M. Simonelig

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

A. Haidar· 1 shared A. Mahoudeau· 1 shared A. Malerba· 1 shared A. Ramat· 1 shared A. Sinz· 1 shared C. Garret· 1 shared C. Ihling· 1 shared C. Rammelt· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

A. Haidar

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Author profile →

3 papers

Recent·Most cited

Germ granule higher-order organization coordinates their different functions

A. Ramat, A. Haidar, C. Garret, M. Simonelig

The paper shows that Drosophila germ granules have a biphasic organization where translation occurs in the outer phase, and mRNA localization depends on their translation status.

bioRxiv · Nov 24, 2023Cell Biology

Guanabenz treatment improves Oculopharyngeal muscular dystrophy phenotype

A. Malerba, F. Roth, P. Harish, J. Dhiab, N. Lu-Nguyen, O. Cappellari, S. Jarmin, A. Mahoudeau, V. Ythier, J. Laine, E. Negroni, E. Abgueguen, M. Simonelig, P. Guedat, V. Mouly, , C. Trollet

This study shows that guanabenz acetate reduces PABPN1 aggregates and improves muscle function in an OPMD mouse model by modulating the UPR.

bioRxiv · Jul 24, 2018 · PreprintPathology

Translational Repression Of The Drosophila nanos mRNA Involves The RNA Helicase Belle And RNA Coating By Me31B And Trailer hitch

M. Gotze, J. Dufourt, C. Ihling, C. Rammelt, S. Pierson, N. Sambrani, C. Temme, A. Sinz, M. Simonelig, E. Wahle

The paper identifies Belle as a novel component of the SRE-dependent repressor complex that contributes to translational repression of nanos mRNA in Drosophila.

bioRxiv · May 24, 2017Biochemistry