Author

A. Mariappan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

J. Gopalakrishnan· 2 shared A. Dilthey· 1 shared A. Islam Pranty· 1 shared A. Mueller-Shiffmann· 1 shared A. Papantonis· 1 shared A. Ramani· 1 shared A. Walker· 1 shared B. Dynlacht· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

J. Gopalakrishnan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deciphering the gene regulatory circuitry governing chemoresistance in Triple-Negative Breast Cancer

R. Lusby, A. Mariappan, Z. Zhang, V. K. Tiwari

This study identifies transcriptional regulatory networks driving chemoresistance in TNBC using single-cell transcriptome data and genetic screens.

bioRxiv · May 5, 2023 · PreprintCancer Biology

Cilium induction triggers differentiation of glioma stem cells

G. Goranci-Buzhala, A. Mariappan, L. Ricci-Vitiani, N. Josipovic, S. Pacion, M. Gottardo, J. Ptok, G. C. Callaini, K. Rajalingam, B. Dynlacht, K. Hadian, A. Papantonis, R. Pallini, J. Gopalakrishnan

This study shows that inducing ciliogenesis in glioma stem cells (GSCs) promotes their differentiation and prevents brain infiltration, suggesting cilium induction as a therapeutic strategy for glioblastoma.

bioRxiv · Dec 23, 2020Cell Biology

SARS-CoV-2 targets cortical neurons of 3D human brain organoids and shows neurodegeneration-like effects

J. Gopalakrishnan, A. Ramani, L. Mueller, P. Niklas Ostermann, E. Gabriel, A. Islam Pranty, A. Mueller-Shiffmann, A. Mariappan, O. Goureau, H. Gruell, A. Walker, M. Andree, S. Hauka, K. Wohlgemuth, H. Omran, , A. Dilthey

This study shows SARS-CoV-2 infects cortical neurons in 3D human brain organoids, causing neurodegeneration-like effects such as Tau mislocalization and neuronal death.

bioRxiv · May 20, 2020Cell Biology