Cell BiologybioRxiv
SARS-CoV-2 targets cortical neurons of 3D human brain organoids and shows neurodegeneration-like effects
J. Gopalakrishnan, A. Ramani, L. Mueller…·A. Dilthey
This study shows SARS-CoV-2 infects cortical neurons in 3D human brain organoids, causing neurodegeneration-like effects such as Tau mislocalization and neuronal death.
DOI 10.15252/embj.2020106230