Selective augmentation of intestinal immunity by CD22-dependent SHP-1 control of β7 integrin expression.
R. Ballet, C. Brandl, N. Feng, J. Berri, J. Cheng, B. Ocon, A. Alborzian Deh Sheikh, A. Marki, C. L. Abram, C. A. Lowell, T. Tsubata, H. B. Greenberg, M. S. Macauley, K. Ley, L. Nitschke, E. Butcher
This study identifies CD22-dependent SHP-1 regulation of β7 integrin expression, showing its role in intestinal immunity and pathogen clearance.
bioRxiv · Jan 31, 2020 · PreprintImmunology