BiochemistrybioRxiv
An intrinsic temporal order of c-Jun N-terminal phosphorylation regulates its activity by orchestrating co-factor recruitment
C. A. Waudby, S. Alvarez-Teijeiro, S. Suppinger…·A. Mylona
The paper shows that c-Jun phosphorylation by JNK occurs in a defined temporal order, leading to distinct functional states that regulate signaling through co-factor recruitment.
DOI 10.1038/s41467-022-33866-w