Author

A. Behrens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Pinto-Fernandez· 2 shared B. M. Kessler· 2 shared C. Heride· 2 shared C. McKinnon· 2 shared D. Komander· 2 shared M. J. Clague· 2 shared M. Katz· 2 shared S. Ioannidis· 2 shared

Activity by Year

2018-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. Pinto-Fernandez

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

An intrinsic temporal order of c-Jun N-terminal phosphorylation regulates its activity by orchestrating co-factor recruitment

C. A. Waudby, S. Alvarez-Teijeiro, S. Suppinger, P. R. Brown, A. Behrens, J. Christodoulou, A. Mylona

The paper shows that c-Jun phosphorylation by JNK occurs in a defined temporal order, leading to distinct functional states that regulate signaling through co-factor recruitment.

bioRxiv · Nov 3, 2021Biochemistry

USP28 deletion and small molecule inhibition destabilises c-Myc and elicits regression of squamous cell lung carcinoma

E. J. Ruiz, A. Pinto-Fernandez, A. P. Turnbull, L. Lan, T. M. Charlton, H. C. Scott, A. Damianou, G. Vere, E. M. Riising, C. Da Costa, W. W. Krajewski, D. Guerin, J. Kearns, S. Ioannidis, M. Katz, , A. Behrens

This study shows that deleting or inhibiting USP28 reduces c-Myc levels and causes regression of lung squamous cell carcinoma in mice and human xenografts.

bioRxiv · Nov 17, 2020Cancer Biology

Dual-view oblique plane microscopy (dOPM)

H. Sparks, L. Dent, C. Bakal, A. Behrens, G. Salbreux, C. Dunsby

This paper introduces a new dual-view oblique plane microscopy technique that improves resolution and reduces shadow artefacts in multi-cellular spheroid imaging.

bioRxiv · Sep 24, 2020Bioengineering

Lack of adaptation to centriolar defects leads to p53-independent microcephaly in the absence of Cep135

J. Gonzalez-Martinez, A. Cwersch, D. Martinez-Alonso, L. R. Lopez, J. Almagro, D. Megias, J. Boskovic, J. Gilabert, O. Grana Castro, A. Pierani, A. Behrens, S. Ortega, M. Malumbres

This study shows that Cep135 loss causes microcephaly in mice through p53-independent mechanisms due to neural progenitor adaptation failure to centriole defects.

bioRxiv · May 7, 2020 · PreprintCell Biology

The deubiquitylase USP9X controls ribosomal stalling

A. Clancy, C. Heride, A. Pinto-Fernandez, A. Kallinos, K. Kayser-Bricker, W. Wang, V. Smith, H. Elcocks, S. Davis, S. Fessler, C. McKinnon, M. Katz, T. Hammonds, N. P. Jones, J. O'Connell, , M. J. Clague

This study identifies USP9X as a deubiquitylase that regulates ZNF598 stability, impacting ribosomal quality control through modulation of di-ribosome resolution.

bioRxiv · Apr 15, 2020Cell Biology

Biofilm/Persister/Stationary Phase Bacteria Cause More Severe Disease Than Log Phase Bacteria II Infection with Persister Forms of Staphylococcus aureus Causes a Chronic Persistent Skin Infection with More Severe Lesion that Takes Longer to Heal and is not Eradicated by the Current Recommended Treatment in Mice

R. Yee, Y. Yuan, C. Brayton, A. T. Leal, J. Feng, W. Shi, A. Behrens, Y. Zhang

bioRxiv · Nov 29, 2018 · PreprintMicrobiology