Combined oncolytic adenovirus carrying MnSOD and mK5 genes both regulated by survivin promoter has synergistic inhibitory effect on gastric cancer
S. Liu, X. Liu, J. Hu, J. Gu, A. Ni, W. Tang
This study constructs two oncolytic adenoviruses carrying mK5 or MnSOD genes under survivin promoter control and shows their combined use significantly inhibits gastric cancer growth in vitro and in vivo.
bioRxiv · Apr 8, 2021Cancer Biology