MicrobiologybioRxiv
PI(3,4,5)P3 allosteric regulation of repressor activator protein 1 controls antigenic variation in trypanosomes
A. O. Touray, R. Rajesh, T. Isebe…·I. Cestari
This study identifies a phosphoinositide signaling system that regulates VSG gene switching in trypanosomes by modulating RAP1's DNA binding activity.
DOI 10.7554/elife.89331