BiochemistrybioRxiv
The role of anionic amino acids in hydrolysis of poly-β-(1,6)-N-acetylglucosamine exopolysaccharides by the biofilm dispersing glycosidase Dispersin B
A. P. Breslawec, S. Wang, C. Li, M. B. Poulin
This study investigates how anionic amino acids in Dispersin B affect PNAG substrate recognition and hydrolysis, showing that D147 enhances catalytic activity with cationic PNAG.
DOI 10.1074/jbc.ra120.015524