Cell BiologybioRxiv
15-PGDH Inhibition Activates the Splenic Niche to Promote Hematopoietic Regeneration
J. N. P. Smith, D. M. Dawson, K. F. Christo…·A. B. Desai
This study shows that inhibiting 15-PGDH enhances splenic support for hematopoietic stem and progenitor cells, improving hematopoietic regeneration after bone marrow transplantation.
DOI 10.1172/jci.insight.143658