Author

A. P. Latham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

B. Zhang· 3 shared A. P. Willard· 1 shared D. A. Sharon· 1 shared L. Zhu· 1 shared S. Ye· 1 shared X. ZhangiD· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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3 shared papersBiophysics

B. Zhang

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Author profile →

3 papers

Recent·Most cited

Microphase Separation Produces Interfacial Environment within Diblock Biomolecular Condensates

A. P. Latham, L. Zhu, D. A. Sharon, S. Ye, A. P. Willard, X. Zhang, B. Zhang

This study uses simulations and experiments to show that diblock polypeptides form interfacial environments due to hydrophilic-hydrophobic residue distribution, affecting condensate stability and hydrogen bonding.

bioRxiv · Mar 30, 2023Biophysics

On the stability and layered organization of protein-DNA condensates

A. P. Latham, B. Zhang

This study uses near-atomistic simulations to investigate the stability and layered organization of protein-DNA condensates, revealing how protein-DNA ratios and interactions influence their structure.

bioRxiv · Aug 22, 2021Biophysics

Consistent Force Field Captures Homolog Resolved HP1 Phase Separation

A. P. Latham, B. Zhang

This paper introduces a force field, MOFF, that accurately models both ordered and disordered proteins and applies it to study HP1 homologs' phase separation behavior.

bioRxiv · Jan 6, 2021Biophysics