BiophysicsbioRxiv
A large disordered region confers a wide spanning volume to vertebrate Suppressor of Fused as shown in a trans-species solution study.
S. Makamte, A. Jabrani, A. Paquelin…·V. Biou
The paper compares the solution structures of SuFu from drosophila, zebrafish, and human, showing that vertebrate SuFu's IDR2 spans a large volume, enabling functional interactions and post-translational modifications.