Author

A. Pautsch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

A. C. W. Pike· 1 shared A. Quigley· 1 shared B. Huang· 1 shared C. S. Tautermann· 1 shared D. B. Sauer· 1 shared E. P. Carpenter· 1 shared F. Stengel· 1 shared G. Chi· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. C. W. Pike

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2 papers

Recent·Most cited

Structural basis of the mechanism and inhibition of a human ceramide synthase

T. C. Pascoa, A. C. W. Pike, C. S. Tautermann, G. Chi, M. Traub, A. Quigley, R. Chalk, S. Stefanic, S. Thamm, A. Pautsch, E. P. Carpenter, G. Schnapp, D. B. Sauer

This study determines the structural mechanism of CerS6, a ceramide synthase, using cryo-EM and biochemical analysis, revealing a ping-pong reaction mechanism and insights into fumonisin B1 inhibition.

bioRxiv · Dec 2, 2023Biochemistry

PolyQ expansion does not alter the Huntingtin-HAP40 complex

B. Huang, Q. Guo, M. L. Niedermeier, J. Cheng, T. Engler, M. Maurer, A. Pautsch, W. Baumeister, F. Stengel, S. Kochanek, R. Fernandez-Busnadiego

This study shows that polyQ expansion in HTT does not change the structure of the HTT-HAP40 complex, as revealed by biophysical and cryo-EM analyses.

bioRxiv · Feb 2, 2021Biophysics