BiochemistrybioRxiv
Characterisation Of The Biflavonoid Hinokiflavone As A Pre-mRNA Splicing Modulator That Inhibits SENP
A. Pawellek, U. Ryder, T. Tammsalu…·A. I. Lamond
This study identifies hinokiflavone as a splicing inhibitor that modulates alternative splicing by inhibiting SUMO protease SENP1 and altering SUMOylation of splicing factors.
DOI 10.7554/elife.27402