Author

A. Peixoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:metabolomics· 3 Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2

Frequent Co-Authors

C. Palmeira· 3 shared J. A. Ferreira· 3 shared J. Soares· 3 shared P. Paulo· 3 shared A. Brandao· 2 shared A. M. Silva· 2 shared A. Miranda· 2 shared C. Gaiteiro· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

C. Palmeira

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

In tissue spatial single-cell metabolomics by coupling mass spectrometry imaging and immunofluorescences

L. Blanc, F. Grelard, M. Tuck, V. Dartois, A. Peixoto, N. Desbenoit

This paper introduces a multimodal imaging workflow combining MALDI-MSI and IF microscopy to enhance spatial single-cell metabolomics, validated on mouse spleen sections.

bioRxiv · Mar 22, 2024 · PreprintBiochemistry

Multilevel Plasticity and Altered Glycosylation Drive Aggressiveness in Hypoxic and Glucose-Deprived Bladder Cancer Cells

A. Peixoto, D. Ferreira, A. Miranda, M. Relvas-Santos, R. Freitas, T. S. Veth, A. Brandao, E. Ferreira, P. Paulo, M. Cardoso, C. Gaiteiro, S. Cotton, J. Soares, L. Lima, F. Teixeira, , J. A. Ferreira

This study identifies hypoxia and glucose deprivation as drivers of aggressiveness in bladder cancer through metabolic adaptation and altered glycosylation.

bioRxiv · Oct 21, 2023Biochemistry

Glycoproteogenomics characterizes the CD44 splicing code driving bladder cancer invasion

c. gaiteiro, J. Soares, M. Relvas Santos, A. Peixoto, D. Ferreira, A. Brandao, E. Fernandes, R. Azevedo, P. Paulo, C. Palmeira, L. Lima, R. Freitas, A. Miranda, H. Osorio, A. M. Silva, , J. A. Ferreira

This study identifies CD44s as a biomarker of poor prognosis in bladder cancer and demonstrates the utility of glycoproteogenomics for characterizing splicing and glycosylation patterns linked to cancer invasion.

bioRxiv · Sep 4, 2021 · PreprintCancer Biology

Metabolomics, Transcriptomics and Functional Glycomics Reveals Bladder Cancer Cells Plasticity and Enhanced Aggressiveness Facing Hypoxia and Glucose Deprivation

A. Peixoto, R. A. Freitas, D. A. Ferreira, M. Relvas-Santos, P. Paulo, M. Cardoso, J. Soares, C. A. Gaiteiro, C. Palmeira, F. Teixeira, R. Ferreira, M. J. Oliveira, A. Silva, L. L. Santos, J. A. Ferreira

This study shows that bladder cancer cells become more aggressive under hypoxia and glucose deprivation through metabolic and glycosylation changes.

bioRxiv · Feb 14, 2021 · PreprintCancer Biology

Type-3 Secretion System-induced pyroptosis protects Pseudomonas against cell-autonomous immunity

E. Eren, R. Planes, J. M. Buyck, P.-J. Bordignon, A. Colom, O. Cunrath, R. F. Dreier, J. C. Santos, V. Duplan-Eche, E. Näser, A. Peixoto, D. Bumann, C. Cougoule, A. Coste, O. Neyrolles, , E. Meunier

This study shows that Pseudomonas aeruginosa uses its Type-3 Secretion System to induce macrophage pyroptosis, escaping immune trapping, while T3SS-deficient strains are captured by inflammasome-mediated immunity.

bioRxiv · May 28, 2019 · PreprintImmunology