A. Silva

Tracking spatial patterns and nocturnal arousal in an undisturbed natural population of the pulse-type weakly electric fish Gymnotus omarorum

The paper develops remote tracking methods for wild electric fish and confirms nocturnal arousal linked to temperature changes.

TLCellClassifier: Machine Learning Based Cell Classification for Bright-Field Time-Lapse Images

TLCellClassifier improves cell detection, tracking, and classification in time-lapse images using CNN, metric learning, and LSTM, outperforming existing tools in accuracy and efficiency.

A flexible fluid delivery system for rodent behavior experiments

The paper introduces an open-source, stepper-motor-based system for precise liquid delivery in rodent behavior experiments and validates its performance in psychophysics tasks and electrophysiology.

NEKL-4 regulates microtubule stability and mitochondrial health in C. elegans ciliated neurons

This study shows NEKL-4 regulates ciliary stability and mitochondrial health in C. elegans ciliated neurons through kinesin activation and mitochondrial homeostasis.

Influenza A virus activates the unfolded protein response and induces the accumulation of insoluble protein aggregates that are essential for efficient viral propagation

The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families

The paper investigates how auxiliary domains in CHD4 modulate its activity, revealing common regulatory mechanisms across chromatin remodelling enzyme families.

Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14 and Sic1 for origin licensing in S. cerevisiae

This study identifies the sequential regulation of Cdc6 phosphorylation by PP2A-Cdc55, Cdc14, and Sic1 in S. cerevisiae to control origin licensing.

Metabolomics, Transcriptomics and Functional Glycomics Reveals Bladder Cancer Cells Plasticity and Enhanced Aggressiveness Facing Hypoxia and Glucose Deprivation

This study shows that bladder cancer cells become more aggressive under hypoxia and glucose deprivation through metabolic and glycosylation changes.

High school Internship Program in Integrated Mathematical Oncology (HIP IMO) - five-year experience at Moffitt Cancer Center

The paper describes a high school internship program in mathematical oncology, detailing its structure, curriculum, and outcomes over five years.

The estrogenic pathway modulates non-breeding female aggression in a teleost fish

This study investigates the role of estrogens and androgens in non-breeding female aggression in the teleost fish Gymnotus omarorum, finding that estrogen inhibition reduces aggression while anti-androgen treatment has no effect.

Seasonal and social factors associated with spacing in a wild territorial electric fish

This study examines seasonal and social factors influencing territory size in wild electric fish, finding that body size and gonadal hormones affect territory size differently across breeding and non-breeding seasons.

Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics

This study identifies unique molecular features of MDSCs using single-cell transcriptomics, revealing a distinct maturation trajectory and novel surface markers for their detection.

Dioecy in plants: an evolutionary dead end? Insights from a population genomics study in the Silene genus

This study uses population genomics to challenge the evolutionary dead end hypothesis of dioecy in Silene species, finding increased genetic diversity and adaptation potential in dioecious species.

Effect of cadmium accumulation on the performance of plants and of herbivores that cope differently with organic defences

This study examines how cadmium accumulation in tomato plants affects two spider-mite species with contrasting responses to organic defences, finding no interaction between metal-based and organic defences.