ImmunologybioRxivPreprint
Type-3 Secretion System-induced pyroptosis protects Pseudomonas against cell-autonomous immunity
E. Eren, R. Planes, J. M. Buyck…·E. Meunier
This study shows that Pseudomonas aeruginosa uses its Type-3 Secretion System to induce macrophage pyroptosis, escaping immune trapping, while T3SS-deficient strains are captured by inflammasome-mediated immunity.
DOI 10.1101/650333