Author

J. Soares

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2

Frequent Co-Authors

A. Peixoto· 3 shared C. Palmeira· 3 shared J. A. Ferreira· 3 shared P. Paulo· 3 shared A. Brandao· 2 shared A. M. Silva· 2 shared A. Miranda· 2 shared C. Gaiteiro· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. Peixoto

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Multilevel Plasticity and Altered Glycosylation Drive Aggressiveness in Hypoxic and Glucose-Deprived Bladder Cancer Cells

A. Peixoto, D. Ferreira, A. Miranda, M. Relvas-Santos, R. Freitas, T. S. Veth, A. Brandao, E. Ferreira, P. Paulo, M. Cardoso, C. Gaiteiro, S. Cotton, J. Soares, L. Lima, F. Teixeira, , J. A. Ferreira

This study identifies hypoxia and glucose deprivation as drivers of aggressiveness in bladder cancer through metabolic adaptation and altered glycosylation.

bioRxiv · Oct 21, 2023Biochemistry

Glycoproteogenomics characterizes the CD44 splicing code driving bladder cancer invasion

c. gaiteiro, J. Soares, M. Relvas Santos, A. Peixoto, D. Ferreira, A. Brandao, E. Fernandes, R. Azevedo, P. Paulo, C. Palmeira, L. Lima, R. Freitas, A. Miranda, H. Osorio, A. M. Silva, , J. A. Ferreira

This study identifies CD44s as a biomarker of poor prognosis in bladder cancer and demonstrates the utility of glycoproteogenomics for characterizing splicing and glycosylation patterns linked to cancer invasion.

bioRxiv · Sep 4, 2021 · PreprintCancer Biology

Metabolomics, Transcriptomics and Functional Glycomics Reveals Bladder Cancer Cells Plasticity and Enhanced Aggressiveness Facing Hypoxia and Glucose Deprivation

A. Peixoto, R. A. Freitas, D. A. Ferreira, M. Relvas-Santos, P. Paulo, M. Cardoso, J. Soares, C. A. Gaiteiro, C. Palmeira, F. Teixeira, R. Ferreira, M. J. Oliveira, A. Silva, L. L. Santos, J. A. Ferreira

This study shows that bladder cancer cells become more aggressive under hypoxia and glucose deprivation through metabolic and glycosylation changes.

bioRxiv · Feb 14, 2021 · PreprintCancer Biology

Membrane Elastic Properties During Neural Progenitor/Neural Stem Cell Differentiation

J. Soares, G. R. d. S. Araujo, C. Santana, D. Matias, V. Moura-Neto, M. Farina, S. Frases, N. B. Viana, L. Romao, H. M. Nussenzveig, B. Pontes

The paper measures membrane tension and bending modulus during neural stem cell differentiation into neurons, astrocytes, and oligodendrocytes, revealing distinct mechanical changes correlated with morphological and molecular transitions.

Cells · May 26, 2020Peer-reviewedBiophysics

Chronic environmentally relevant levels of Simvastatin induces non-monotonic responses in Zebrafish (Danio rerio)

S. Barros, R. Montes, J. B. Quintana, R. Rodil, A. Andre, A. Capitao, J. Soares, M. M. Santos, T. Neuparth

This study investigates the chronic effects of simvastatin on zebrafish at environmentally relevant concentrations, finding non-monotonic dose responses in embryonic development, biochemistry, and gene expression.

Aquatic Toxicology · Aug 1, 2018Peer-reviewedPharmacology & Toxicology