Author

A. Piapi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

C. Thevanesan· 3 shared G. Kildisiute· 3 shared M. D. Young· 3 shared M. Haniffa· 3 shared C. Burke· 2 shared D. Rampling· 2 shared E. Khabirova· 2 shared E. Prigmore· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

C. Thevanesan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transcriptional signals of dedifferentiation in human cancer

G. Kildisiute, M. Kalyva, R. Elmentaite, S. van Dongen, C. Thevanesan, A. Piapi, K. Ambridge, E. Prigmore, M. Haniffa, S. A. Teichmann, K. Straathof, I. Cortes-Ciriano, S. Behjati, M. D. Young

This study examines dedifferentiation in cancer using single-cell atlases, finding that adult cancers do not revert to an embryonic state but retain foetal signals, while childhood cancers show universal foetal state features.

bioRxiv · Nov 28, 2022 · PreprintCancer Biology

Exploration of the single-cell transcriptomic landscape identifies aberrant glomerular cell crosstalk in a murine model of WT1 kidney disease

J. C. Chandler, D. J. Jafree, S. Malik, G. Pomeranz, M. Ball, M. Kolatsi-Joannou, A. Piapi, W. J. Mason, A. S. Woolf, P. J. Winyard, A. S. Mason, A. M. Waters, D. A. Long

This study uses single-cell RNA sequencing to identify disrupted cell-cell communication in a mouse model of WT1 kidney disease, highlighting non-immunological pathology and suggesting vascular-targeted therapies.

bioRxiv · Oct 11, 2022 · PreprintCell Biology

Tumor to normal single cell mRNA comparisons reveal a pan-neuroblastoma cancer cell

G. Kildisiute, W. M. Kholosy, M. D. Young, K. Roberts, R. Elmentaite, S. R. van Hooff, E. Khabirova, A. Piapi, C. Thevanesan, E. Bugallo Blanco, C. Burke, L. Mamanova, P. Lijnzaad, T. Margaritis, F. C. P. Holstege, , S. Behjati

The paper compares tumor and normal single-cell mRNA data to show neuroblastoma cells resemble fetal sympathoblasts across diverse samples.

bioRxiv · Jun 22, 2020Cancer Biology

Cellular mRNA signals in human kidney tumors

M. D. Young, T. J. Mitchell, L. M. Custers, T. Margaritis, F. Morales, K. Kwakwa, E. Khabirova, G. Kildisiute, T. R. Oliver, R. R. d. Krijger, M. M. v. d. Heuvel-Eibrink, F. Comitani, A. Piapi, E. B. Blanco, C. Thevanesan, , Holste

This study analyzes mRNA signals in 1,300 kidney tumors to determine their differentiation state and origin, finding that childhood tumors show fetal signals while most adult tumors do not, with exceptions in certain cancer types.

bioRxiv · Mar 19, 2020Cancer Biology