Author

M. Kalyva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

I. Cortes-Ciriano· 2 shared A. C. Darby· 1 shared A. Gioti· 1 shared A. Kampouraki· 1 shared A. Mullally· 1 shared A. Piapi· 1 shared B. Kamaz· 1 shared C. R. Reilly· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

I. Cortes-Ciriano

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Author profile →

3 papers

Recent·Most cited

Transcriptional signals of dedifferentiation in human cancer

G. Kildisiute, M. Kalyva, R. Elmentaite, S. van Dongen, C. Thevanesan, A. Piapi, K. Ambridge, E. Prigmore, M. Haniffa, S. A. Teichmann, K. Straathof, I. Cortes-Ciriano, S. Behjati, M. D. Young

This study examines dedifferentiation in cancer using single-cell atlases, finding that adult cancers do not revert to an embryonic state but retain foetal signals, while childhood cancers show universal foetal state features.

bioRxiv · Nov 28, 2022 · PreprintCancer Biology

Reconstructing the lineage histories and differentiation trajectories of individual cancer cells in JAK2-mutant myeloproliferative neoplasms

D. Van Egeren, J. Escabi, M. Nguyen, S. Liu, C. R. Reilly, S. Patel, B. Kamaz, M. Kalyva, D. J. DeAngelo, I. Galinsky, M. Wadleigh, E. S. Winer, M. R. Luskin, R. M. Stone, J. S. Garcia, , S. Hormoz

This study reconstructs the lineage histories and differentiation trajectories of JAK2-mutant HSCs in MPN patients, finding the mutation occurs decades before diagnosis and drives exponential growth of mutated HSC populations.

bioRxiv · Aug 24, 2020Cancer Biology

Functional genomics of a symbiotic community: shared traits in the olive fruit fly gut microbiota

F. Blow, A. Gioti, I. B. Goodhead, M. Kalyva, A. Kampouraki, J. Vontas, A. C. Darby

This study investigates the functional genomics of the olive fruit fly gut microbiota, identifying shared traits and genetic exchanges that support symbiosis.

bioRxiv · Apr 8, 2019Evolutionary Biology