Targeting C5aR1 signaling reduced neutrophil extracellular traps and ameliorates COVID-19 pathology
B. M. Silva, F. P. Veras, G. Gomes, S. Cambier, G. Silva, A. Quadros, D. Caetite, D. Nascimento, C. Silva, J. Silva, S. Damasceno, A. Schneider, F. Beretta, S. Batah, I. Castro, , T. M. Cunha
This study shows that inhibiting C5aR1 signaling reduces neutrophil extracellular traps and improves lung pathology in COVID-19.
bioRxiv · Jul 3, 2022Immunology