Ultrasound inhibits SARS-CoV-2 infectivity in vitro
F. P. Veras, G. Nakamura, M. A. Pereira-da-Silva…·O. M. Bruno
This study shows ultrasound can reduce SARS-CoV-2 infectivity in vitro without causing heat or cavitation.
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6 papers
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F. P. Veras, G. Nakamura, M. A. Pereira-da-Silva…·O. M. Bruno
This study shows ultrasound can reduce SARS-CoV-2 infectivity in vitro without causing heat or cavitation.
F. P. Veras, G. F. Gomes, B. M. Silva…·F. Q. Cunha
This study shows that DNase I treatment reduces NETs and organ injury in a COVID-19 mouse model.
A. C. Puhl, G. F. Gomes, S. Damasceno…·S. Ekins
This study tests FDA-approved kinase inhibitors against SARS-CoV-2 in vitro and in vivo, finding that vandetanib reduces inflammatory cytokines and mitigates lung inflammation in infected mice without reducing viral load.
A. C. Puhl, G. F. Gomes, S. Damasceno…·S. Ekins
Pyronaridine reduces SARS-CoV-2 viral load and lung pathology in mice, with in vitro inhibition of viral PLpro and host kinase CAMK1.
M. C. Pontelli, I. A. Castro, R. B. Martins…·E. Arruda
This study investigates SARS-CoV-2 infection of human lymphomononuclear cells in vitro and in vivo, finding that monocytes, B cells, and T cells are susceptible to infection and viral replication.