Author

I. Castro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Ecology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Beja-Pereira· 1 shared A. C. G. Salina· 1 shared A. Fabro· 1 shared A. J. Munoz-Pajares· 1 shared A. Martins· 1 shared A. Munoz-Merida· 1 shared A. Quadros· 1 shared A. Schneider· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPlant Biology

A. Beja-Pereira

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Loss of IRF5 increases ribosome biogenesis leading to alterations in mammary gland architecture and metastasis

Z. Brune, D. Li, S. Song, D. I. Li, I. Castro, R. Rasquinha, M. Rice, Q. Guo, K. Kampta, M. Moss, M. Lallo, E. Pimenta, C. Somerville, M. Lapan, V. Nelson, , B. J. J. Barnes

This study shows that loss of IRF5 predicts metastasis and survival in breast cancer and reveals its role in regulating ribosome biogenesis and tumor progression.

bioRxiv · May 1, 2023 · PreprintCancer Biology

Targeting C5aR1 signaling reduced neutrophil extracellular traps and ameliorates COVID-19 pathology

B. M. Silva, F. P. Veras, G. Gomes, S. Cambier, G. Silva, A. Quadros, D. Caetite, D. Nascimento, C. Silva, J. Silva, S. Damasceno, A. Schneider, F. Beretta, S. Batah, I. Castro, , T. M. Cunha

This study shows that inhibiting C5aR1 signaling reduces neutrophil extracellular traps and improves lung pathology in COVID-19.

bioRxiv · Jul 3, 2022Immunology

Evidence of post-domestication hybridization and adaptive introgression in Western European grapevine varieties

S. Freitas, M. A. Gazda, M. Rebelo, A. J. Munoz-Pajares, C. M. Vila-Vicosa, A. Munoz-Merida, L. M. Goncalves, D. Azevedo-Silva, S. Afonso, I. Castro, P. H. Castro, M. Sottomayor, A. Beja-Pereira, J. Tereso, N. Ferrand, , H. Azevedo

This study uses whole genome resequencing to show post-domestication hybridization and adaptive introgression in Western European grapevine varieties, with strong signals in Iberian varieties.

bioRxiv · Mar 3, 2021Plant Biology

Precision as a metric for acoustic survey design using occupancy or spatial capture-recapture

J. Juodakis, I. Castro, S. Marsland

This paper evaluates precision as a metric for assessing acoustic survey design in occupancy and spatial capture-recapture frameworks, showing it better captures tradeoffs than stage-specific metrics.

bioRxiv · Sep 30, 2020 · PreprintEcology