ImmunologybioRxiv
A HYPOMETABOLIC DEFENSE STRATEGY AGAINST PLASMODIUM INFECTION
S. Ramos, T. W. Ademolue, E. Jentho…·M. P. Soares
The paper shows that Plasmodium infection induces hypoglycemia in mice through heme-driven suppression of hepatic glucose production, which limits parasite growth but promotes gametocyte production.
DOI 10.1016/j.cmet.2022.06.011