Author

E. Jentho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

J. Guerra· 2 shared M. P. Soares· 2 shared R. Martins· 2 shared S. Weis· 2 shared A. Eugster· 1 shared A. G. Sousa· 1 shared A. R. Carlos· 1 shared B. Novakovic· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

J. Guerra

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2 papers

Recent·Most cited

A HYPOMETABOLIC DEFENSE STRATEGY AGAINST PLASMODIUM INFECTION

S. Ramos, T. W. Ademolue, E. Jentho, Q. Wu, J. Guerra, R. Martins, G. Pires, S. Weis, A. R. Carlos, I. Mahu, E. Seixas, D. Duarte, F. Rajas, S. Cardoso, A. G. Sousa, , M. P. Soares

The paper shows that Plasmodium infection induces hypoglycemia in mice through heme-driven suppression of hepatic glucose production, which limits parasite growth but promotes gametocyte production.

bioRxiv · Sep 8, 2021Immunology

Heme induces innate immunity memory

E. Jentho, B. Novakovic, C. C. Ruiz-Moreno, I. Kourtzelis, R. Martins, T. Chavakis, M. P. Soares, L. Kalafati, J. Guerra, F. Roestel, P. Bohm, M. Godmann, T. Grinenko, A. Eugster, M. Beretta, , S. Weis

This study shows heme induces trained immunity in human and murine cells, leading to long-term protection against bacterial sepsis through epigenetic and transcriptional changes.

bioRxiv · Dec 12, 2019 · PreprintImmunology