Author

A. R. Howell

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Inguva· 1 shared A. J. Firestone· 1 shared A. Long· 1 shared B. F. Cravatt· 1 shared B. Huang· 1 shared C. L. Henry· 1 shared J. R. Remsberg· 1 shared K. M. Lum· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Inguva

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1 paper

Recent·Most cited

Cancer BiologybioRxivMay 21, 2020

ABHD17 enzymes regulate dynamic plasma membrane palmitoylation and N-Ras-dependent cancer growth

J. R. Remsberg, R. M. Suciu, N. A. Zambetti…·B. F. Cravatt

This study identifies ABD957, a selective ABHD17 inhibitor, which disrupts N-Ras depalmitoylation and inhibits NRAS-mutant AML growth, suggesting potential as a targeted therapy.

DOI 10.1038/s41589-021-00785-8

humanproteomics

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