BiochemistrybioRxivPreprint
α1A-adrenoceptor inverse agonists and agonists modulate receptor signalling through a conformational selection mechanism
P. R. Gooley, F. Wu, L. M. Williams…·D. J. Scott
This study shows how different ligands modulate the conformational states of the α1A-adrenoceptor through a conformational selection mechanism, as revealed by NMR analysis of labeled receptor mutants.
DOI 10.1101/866475