MicrobiologybioRxiv
Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
A. Madhavan, A. K B, A. Raj Pushparajan…·R. Ajay Kumar
The paper shows that ZBTB25 interacts with HDAC1 in MTB-infected macrophages, and inhibiting this interaction promotes autophagy and kills the pathogen.
DOI 10.1128/msphere.00036-21