Development of Ingenui-T, a Novel Vein-to-Vein Solution for Rapid Autologous CAR T-Cell Manufacturing Starting From Whole Blood, for the Treatment of Autoimmune Diseases
D. Anaya, B. Kwong, S. Park, S. Biswas, J. Jeevan, M. Strobach, N. Khoshnoodi, A. Register, T. Klasson, S. Foos-Russ, J. Zeng, J. Banuelos, C. Gibson, J. Bravo, J. Flandez, , K. Walker
This paper introduces Ingenui-T, a method for rapid CAR T-cell manufacturing from whole blood, showing comparable or better functional activity than conventional methods.
bioRxiv · Jan 24, 2024 · PreprintImmunology