ImmunologybioRxiv
Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium
G. Taylor, H.-I. Huang, B. E. Fee…·G. E. Hammer
This study shows that Irgm1 deficiency causes myeloid cell dysfunction in the colon and increased susceptibility to Citrobacter rodentium infection, independent of intracellular killing.
DOI 10.1371/journal.ppat.1008553