Author

B. A. Vallance

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 5 Assay:proteomics· 3 Assay:metagenomics· 2

Frequent Co-Authors

A. F. Buckley· 1 shared A. F. Rosenberg· 1 shared A. R. Rogala· 1 shared A. S. Gulati· 1 shared A. Schoenborn· 1 shared B. Cai· 1 shared B. E. Fee· 1 shared C. E. Moseley· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. F. Buckley

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5 papers

Recent·Most cited

Turicibacterales protect mice from severe Citrobacter rodentium infection

K. L. Hoek, K. G. McClanahan, Y. L. Latour, N. Shealy, M. B. Piazuelo, B. A. Vallance, M. X. Byndloss, D. Olivares-Villagomez, K. T. Wilson

This study shows that Turicibacterales, specifically Turicibacter sanguinis, protect mice from severe Citrobacter rodentium infection by reducing susceptibility when present.

bioRxiv · Apr 25, 2023 · PreprintMicrobiology

A Non-redundant Role for T cell-derived IL-22 in Antibacterial Defense of Colonic Crypts

C. T. Weaver, C. L. Zindl, S. J. Witte, V. A. Laufer, M. Gao, Z. Yue, D. J. Silberger, S. N. Harbour, J. R. Singer, D. Pham, C. E. Moseley, B. Cai, H. Turner, F. E. Lund, B. A. Vallance, , R. D. Hatton

This study shows that T cell-derived IL-22 is essential for antibacterial defense and damage control in intestinal crypts, despite ongoing ILC3-derived IL-22 production.

bioRxiv · May 11, 2021 · PreprintImmunology

AN INULIN-TYPE FRUCTAN ENRICHED EXCLUSIVE ENTERAL NUTRITION FORMULA SUPPRESSES COLITIS THROUGH GUT MICROBIOME MODULATION AND PROMOTING EXPANSION OF ANTI-INFLAMMATORY T CELL SUBSETS

G. R. Healey, K. Tsai, D. J. Lisko, L. Cook, B. A. Vallance, K. Jacobson

This paper shows that an inulin-type fructan-enriched enteral nutrition formula reduces colitis in mice by modulating the gut microbiome and increasing anti-inflammatory T cell subsets.

bioRxiv · Feb 2, 2021 · PreprintMicrobiology

Commensal bacterial-derived retinoic acid primes host defense to intestinal infection

T. Alenghat, V. Woo, E. M. Eshleman, J. Whitt, S. Hashimoto-Hill, S.-e. Wu, L. Engleman, T. Rice, R. Karns, B. A. Vallance

This study identifies retinoic acid (RA) as a microbiota-derived metabolite that enhances intestinal defense against infection by modulating host gene expression.

bioRxiv · Jan 27, 2021Microbiology

Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium

G. Taylor, H.-I. Huang, B. E. Fee, N. Youssef, V. Cantillana, A. Schoenborn, A. R. Rogala, A. F. Buckley, B. A. Vallance, A. S. Gulati, G. E. Hammer

This study shows that Irgm1 deficiency causes myeloid cell dysfunction in the colon and increased susceptibility to Citrobacter rodentium infection, independent of intracellular killing.

bioRxiv · Mar 26, 2019Immunology