Author

A. Samad

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

D. Horn· 1 shared F. Zahedifard· 1 shared M. C. Field· 1 shared M. Zoltner· 1 shared N. Zhang· 1 shared R. J. Wall· 1 shared

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2024-2024 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

D. Horn

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1 paper

Recent·Most cited

Targeted protein degradation of the CPSF complex by benzoxaboroles through sumoylation

N. Zhang, A. Samad, F. Zahedifard, R. J. Wall, D. Horn, M. Zoltner, M. C. Field

This study identifies CPSF3 as a target of benzoxaboroles in trypanosomatids, showing that BoBs induce sumoylation-dependent degradation of CPSF complex members, leading to reduced mRNA levels.

bioRxiv · Mar 11, 2024 · PreprintCell Biology