Author

F. Zahedifard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

M. Zoltner· 2 shared A. N. Volkov· 1 shared A. Zikova· 1 shared B. Stijlemans· 1 shared C. Hierro-Yap· 1 shared D. Arbon· 1 shared H. Sulzen· 1 shared J. Mach· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

M. Zoltner

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Beyond the VSG Layer: Exploring the Role of Intrinsic Disorder in the Invariant Surface Glycoproteins of African Trypanosomes

H. Sulzen, A. N. Volkov, R. Geens, F. Zahedifard, B. Stijlemans, M. Zoltner, S. Magez, Y. G.-J. Sterckx, S. Zoll

This study investigates the role of intrinsic disorder in invariant surface glycoproteins (ISGs) of African trypanosomes, showing they can switch between compact and elongated conformers to balance immune evasion and host interaction.

PLOS Pathogens · Apr 22, 2024Peer-reviewedBiochemistry

Repurposing of mitochondria-targeted tamoxifen: Novel anti-cancer drug exhibits potent activity against major protozoan and fungal pathogens.

D. Arbon, K. Zeniskova, K. Subrtova, J. Mach, J. Stursa, M. Machado, F. Zahedifard, T. Lestinova, C. Hierro-Yap, J. Neuzil, P. Volf, M. Ganter, M. Zoltner, A. Zikova, L. Werner, R. Sutak

This paper demonstrates that MitoTam, a mitochondria-targeted tamoxifen analog, effectively kills various pathogens including fungi, Plasmodium falciparum, and trypanosomatid parasites in vitro and in vivo.

bioRxiv · Mar 24, 2022 · PreprintMicrobiology