Fine-tuning of Epithelial EGFR signals Supports Coordinated Mammary Gland Development
A. Samocha, H. Doh, V. Sitarama, Q. Nguyen, O. Gbenedio, J. Rudolf, W. Eckalbar, A. Barczak, Y. Miao, C. Garcia, D. Lawson, Z. Werb, K. Kessenbrock, P. Depeille, J. Roose
This study shows that Rasgrp1 fine-tunes EGFR signals in mammary epithelial cells to regulate development during puberty, with in vitro and in vivo effects on proliferation, branching, and cellularity.
bioRxiv · Sep 10, 2020 · PreprintCell Biology