BioengineeringbioRxivPreprint
AbNatiV: VQ-VAE-based assessment of antibody and nanobody nativeness for hit selection, humanisation, and engineering
A. Ramon, M. Ali, M. Atkinson…·P. Sormanni
AbNatiV assesses antibody and nanobody nativeness using a VQ-VAE model, enabling hit selection, humanisation, and engineering with improved performance over conventional methods.