Deletion of FNDC5/Irisin modifies murine osteocyte function in a sex-specific manner
A. Shimonty, F. Pin, M. Prideaux, G. Peng, J. Huot, H. Kim, C. j. Rosen, B. M. Spiegelman, L. F. Bonewald
This study shows that irisin deletion affects murine osteocyte function differently in males and females, with protection in females under calcium deficiency and increased bone loss in males.
bioRxiv · Nov 6, 2023Physiology