A Human Breast Cell Atlas Mapping the Homeostatic Cellular Shifts in the Adult Breast
A. D. Reed, S. Pensa, A. Steif, J. Stenning, D. Kunz, P. He, A.-J. Twigger, K. Kania, R. Barrow, I. Goulding, J. Gomm, L. Jones, J. Marioni, W. T. Khaled
This study creates a Human Breast Cell Atlas using scRNA-seq from 55 donors, identifying 41 cell subclusters and showing how factors like age and BRCA mutations affect breast homeostasis and immune cell states.
bioRxiv · Apr 21, 2023 · PreprintCancer Biology